| | | | | Volume of issue | | |
|---|
| Nr. | | Issuing country | Subject of commemoration | Date of issue | BU | Proof | | Details |
|---|
| CC. 397 | | Portugal | Portuguese Presidency of the Council of the European Union | 04.01.2021 | 504.982 | 4.997 | |  |
| CC. 398 | | Germany | Saxony Anhalt " Cathedral of Magdeburg " | 26.01.2021 | 30.218.500 | 215.400 | | |
| CC. 399 | | San Marino | The 450th anniversary of the birth of Caravaggio | 01.03.2021 | 54.000 | 2.400 | | |
| CC. 400 | | Spain | Toledo | 10.03.2021 | 3.994.010 | 5.990 | | |
| CC. 401 | | France | UNICEF | 16.03.2021 | 6.510.000 | 10.000 | | |
| CC. 402 | | Finland | Journalism and Open Communication Supporting the Finnish Democracy | 14.04.2021 | 794.000 | 6.000 | | |
| CC. 403 | | Luxembourg | The 100th anniversary of the Grand Duke Jean | 19.04.2021 | 330.000 | 3.500 | | |
| CC. 404 | | Luxembourg | The 40th anniversary of the marriage of Grand Duke Henri | 19.04.2021 | 330.000 | 3.500 | | |
| CC. 405 | | Greece | 200 years since the Greek Revolution | 22.04.2021 | 1.490.000 | 10.000 | | |
| CC. 406 | | Portugal | Tokyo Olympics | 18.05.2021 | 504.994 | 4.998 | | |
| CC. 407 | | Lithuania | Žuvintas Biosphere Reserve | 19.05.2021 | 500.000 | 0 | | |
| CC. 408 | | Estonia | Finno-Ugric peoples | 16.06.2021 | 1.000.000 | 0 | | |
| CC. 409 | | Vatican | The 450th anniversary of the birth of Caravaggio | 25.06.2021 | 75.000 | 9.300 | | |
| CC. 410 | | Belgium | The 100th anniversary of the constitution of the Belgium-Luxembourg Economic Union (BLEU) | 07.07.2021 | 150.000 | 5.000 | | |
| CC. 411 | | Malta | Heroes of the Pandemic | 02.08.2021 | 72.500 | 0 | | |
| CC. 412 | | Finland | The 100-year autonomy of Åland | 13.08.2021 | 794.000 | 6.000 | | |
| CC. 413 | | Italy | 150th Anniversary of the institution of Rome Capital of Italy | 16.08.2021 | 2.991.500 | 8.500 | | |
| CC. 414 | | San Marino | The 550th anniversary of the birth of Albrecht Dürer | 27.08.2021 | 54.000 | 2.400 | | |
| CC. 415 | | Lithuania | Dzūkija | 09.09.2021 | 500.000 | 0 | | |
| CC. 416 | | France | Olympic Games Paris 2024 (Marianne) | 21.09.2021 | 500.000 | 10.000 | | |
| CC. 418 | | Latvia | The 100th anniversary of Latvia’s international recognition de iure | 05.10.2021 | 412.000 | 0 | | |
| CC. 419 | | Monaco | 10th anniversary of the marriage of Prince Albert II and Princess Charlene | 06.10.2021 | 0 | 15.000 | | |
| CC. 420 | | Estonia | The Estonian national animal – the wolf | 20.10.2021 | 1.000.000 | 0 | | |
| CC. 421 | | Slovenia | The 200th anniversary of the establishment of Provincial Museum for Carniola, the first museum in Slovenia | 25.10.2021 | 997.000 | 3.000 | | |
| CC. 422 | | Malta | Maltese prehistoric temples of Tarxien | 26.10.2021 | 181.000 | 0 | | |
| CC. 423 | | Vatican | The 700th anniversary of the death of Dante Alighieri | 26.10.2021 | 75.000 | 9.300 | | |
| CC. 424 | | Belgium | The 500th anniversary of the appearance of the ordinance of the second period of coin issuance during the reign of Charles V | 27.10.2021 | 150.000 | 5.000 | | |
| CC. 425 | | Italy | Healthcare professionals | 26.11.2021 | 4.991.500 | 8.500 | | |
| CC. 426 | | Slovakia | The 100th anniversary of the birth of Alexander Dubček | 26.11.2021 | 995.800 | 4.200 | | |
| CC. 427 | | Andorra | Our Lady of Meritxell | 15.12.2021 | 70.000 | 3.750 | | |
| CC. 428 | | Andorra | Taking care of our seniors | 15.12.2021 | 70.000 | 0 | | |
